At Best Startup California we track over 300,000 Californian startups and over 1,500,000 people who hold key positions in these companies. We use this directory of startups to highlight top employees, founders and organisations we think deserve more appreciation than they are currently getting.
We’ve ranked the top 87 Biotechnology companies in San Jose, California. The companies, startups and institutions listed in this article are all exceptional companies, well worth a follow. We have included links to their websites, socials and CrunchBase (if you’re interested in their financials).
We selected the organisations listed in this article based on:
- Track record
- Executive leadership
- Market share
- Innovation
- ESG rating
Our Data – We source our data from OSINT (open source intelligence) and public directories such as Crunchbase, SemRush and many more. The data from these sources should be treated with a degree of caution and verified yourself.
Top Biotechnology Companies & Startups (San Jose, California)
Rani Therapeutics
Rani Therapeutics develops bio-therapeutics technology for the oral delivery of large drug molecules.
Founder(s): Mir Imran
Location: San Jose, California, United States
Industries: Biotechnology, Pharmaceutical, Therapeutics
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Aridis Pharmaceuticals
Aridis is a biopharmaceutical company focused on the development of novel, differentiated therapies for infectious diseases.
Founder(s): Eric Patzer, Vu L. Truong
Location: San Jose, California, United States
Industries: Biotechnology, Content Discovery, Health Care, Pharmaceutical
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Loop Genomics
Loop Genomics is a platform technology for long-read DNA sequencing.
Founder(s): Tuval Ben Yehezkel
Location: San Jose, California, United States
Industries: Biotechnology, Genetics, Information Technology, Medical
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Restoration Robotics
Restoration Robotics develops the only computer-assisted, physician-controlled robotic system to harvest follicular units.
Founder(s): Fred Moll, M.D, Philip Gildenberg
Location: San Jose, California, United States
Industries: Beauty, Biotechnology, Medical Device, Robotics
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Cellworks
Cellworks is a life sciences technology company involved in drug and bio-marker discovery and researches in therapeutic areas.
Founder(s): Pradeep Fernandes, Shireen Vali, Taher Abbasi
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Life Science, Pharmaceutical, Therapeutics
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LOLIWARE
LOLIWARE is an award-winning materials tech company dedicated to replacing single-use plastics with seaweed.
Founder(s): Leigh Ann Tucker, Sea Briganti
Location: San Jose, California, United States
Industries: Advanced Materials, Biotechnology, GreenTech, Sustainability
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Ablative Solutions
Ablative Solutions is a medical device firm that offers an alternative to surgical renal denervation for treating hypertension.
Founder(s): David Fischell, Tim Fischell
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Medical Device
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dNovo Bio
Dnovobio is a developer of a direct reprogramming technology intended to create any cell, tissue, or organ on demand.
Founder(s): Ernesto Lujan
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Medical
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Reviva Pharmaceuticals
Reviva Pharmaceuticals is a clinical-stage pharmaceutical company developing innovative therapies.
Founder(s): Laxminarayan Bhat
Location: San Jose, California, United States
Industries: Biopharma, Biotechnology, Genetics, Health Care, Pharmaceutical
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Labcyte
Labcyte is the maker of Echo Acoustic Liquid Handling systems for life sciences.
Founder(s): Richard Ellson
Location: San Jose, California, United States
Industries: Alternative Medicine, Biotechnology, Life Science, Pharmaceutical
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Venclose
Venclose is a medical technology company that develops solutions for the treatment of venous insufficiency.
Founder(s): Brady Esch
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Medical, Medical Device
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Apostle
Apostle Inc is a provider of innovative technologies and services for public health and life sciences.
Founder(s): Bo Zhang, David Ge, Xin Guo
Location: San Jose, California, United States
Industries: Biopharma, Biotechnology, Health Care, Health Diagnostics, Medical Device
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Chronix Biomedical
Chronix Biomedical is a molecular diagnostics company developing blood tests for monitoring minimal residual disease in cancer patients.
Founder(s): Ekkehard Schütz, Howard Urnovitz, John DiPietro
Location: San Jose, California, United States
Industries: Biotechnology, Health Diagnostics, Medical
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VitalConnect
VitalConnect is a wearable biosensor technology for wireless hospital and remote patient monitoring.
Founder(s): Nersi Nazari, Stephen Zadig
Location: San Jose, California, United States
Industries: Analytics, Biotechnology, Health Care, Medical Device, Wearables
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Elevai Labs
Elevai Labs is a biotechnology company that develops regenerative skin care applications.
Founder(s): BRAEDEN WILLIAM LICHTI, Hatem Abou-Sayed, Jordan Plews
Location: San Jose, California, United States
Industries: Beauty, Biotechnology, Cosmetics
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Shield Bio
Shield Bio – using ultra-fast sequencing to prevent antibiotic resistance
Founder(s): Fred Turner, Sam Parlett
Location: San Jose, California, United States
Industries: Biotechnology, Genetics, Health Care, Health Diagnostics
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Da Zen Theranostics
Da Zen Theranostics develop a product that can target cancer cells, function as a contrast agent to improve the visibility of cancer cells.
Founder(s): Leland W.K. Chung
Location: San Jose, California, United States
Industries: Biotechnology, Therapeutics
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Intrapace
Intrapace develops a novel implantable system to treat obesity.
Founder(s): Mir Imran
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Health Diagnostics
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Kolo Medical
Kolo Medical is the world leader in the next generation of semiconductor ultrasound transducer technology.
Founder(s): Bin Qi
Location: San Jose, California, United States
Industries: Biotechnology, Electronics, Health Care, Manufacturing
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Fe3 Medical
Fe3 Medical develops a drug delivery technology for non-toxic iron transportation across the skin for patients with iron-deficiency anemia.
Founder(s): Katherine Aldred
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Medical
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Reactive Medical Labs
Reactive Medical Labs is a biotechnology company developing regenerative skincare applications.
Founder(s): Braeden Lichti, Hatem Abou-Sayed, Jordan Plews
Location: San Jose, California, United States
Industries: Beauty, Biopharma, Biotechnology, Pharmaceutical
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Baxano
Baxano develops minimally-invasive tools to restore spine function and preserve healthy tissues.
Founder(s): Jeffery Bleich
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Medical Device
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zPREDICTA
The mission of zPREDICTA is to automate drug development.
Founder(s): Julia Kirshner, Mukti Parikh
Location: San Jose, California, United States
Industries: Biotechnology, Health Care
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MIODx
MIODx, a company working on biomarker diagnostics.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Medical Device
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H2OPTX, Inc
H2OPTX provides solutions for full 3D chemical imaging of solid dosage formulations.
Founder(s): Rudy Hofmeister
Location: San Jose, California, United States
Industries: Biotechnology, Chemical, Health Care, Life Science, Semiconductor
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Synchronicity Pharma
Synchronicity Pharma is a biotech company focused on transformative therapies designed to leverage circadian rhythm biology.
Founder(s): Joseph S. Takahashi, Ron Evans
Location: San Jose, California, United States
Industries: Biopharma, Biotechnology, Therapeutics
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Mendel.ai
Mendel.ai transforms unstructured EMR data and clinical literature into comprehensive and compliant analytics-ready data.
Founder(s): Karim Galil, Ruchi Deshpande, Wael Salloum
Location: San Jose, California, United States
Industries: Analytics, Artificial Intelligence, Biotechnology, Clinical Trials, Computer Vision, Data Visualization, Health Care, Life Science, Machine Learning, Medical
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Single Cell Technology, Inc.
Single Cell Technology has developed a technology for analyzing antibodies and mRNA from cells called AbTheneum.
Founder(s): Chun-Nan Chen
Location: San Jose, California, United States
Industries: Analytics, Biotechnology, Health Care
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AbboMax, Inc
AbboMax, a biotechnology platform, is an antibody product and service provider.
Founder(s): Kelly Zhou
Location: San Jose, California, United States
Industries: Biotechnology, Customer Service, Health Care, Manufacturing, Pharmaceutical
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NeVap Inc
NeVap is a medical device company that specializes in developing infection control devices.
Founder(s): Benjamin Wang
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Medical Device, Pollution Control
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OncoHealth
OncoHealth designs screening devices that detects and diagnoses cancer.
Founder(s): Shuling Cheng, Winnie Wan
Location: San Jose, California, United States
Industries: Biopharma, Biotechnology, Health Care, Health Diagnostics, Life Science
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Ariosa Diagnostics
Ariosa Diagnostics is a molecular diagnostics company focused on improving patient care.
Founder(s): Ken Song
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Health Diagnostics, Medical
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Cipherome
Cipherome is a biotech company that finds the drug that works for each individual.
Founder(s):
Location: San Jose, California, United States
Industries: Biopharma, Biotechnology, Health Care
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Viropro
Viropro a public company incorporated under the laws of the state of Nevada, specializes in cell line and biopharmaceutical process
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Manufacturing, Medical
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Project Umami
Bioscience software tools for Students and Scientists.
Founder(s): Richard Bernardino
Location: San Jose, California, United States
Industries: Apps, Biotechnology, Education, Product Research, Software
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GenPharm International
GenPharm International is a develops and commercializes HuMAb-Mouse transgenic animal technology.
Founder(s): Larry Bock
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Medical
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Cellsonics
Cellsonics is setting new standards with single-cell sample preparation.
Founder(s): Steve Levers, Vibhu Vivek
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Medical
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NDS Surgical Imaging
NDS Surgical Imaging is a manufacturer of medical imaging and informatics systems for operative and interventional suites.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, DSP, Health Care, Medical, Medical Device
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ProTrials Research
ProTrials Research is a biotechnology firm that provides clinical operations professionals and services.
Founder(s): Inger Arum, Jodi Andrews
Location: San Jose, California, United States
Industries: Biotechnology
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BatchX
End-to-end bioinformatics platform for your custom analyses.
Founder(s): David Castillo Rodríguez, Ignacio Del Valle Alles, Prathik Gadde
Location: San Jose, California, United States
Industries: Bioinformatics, Biotechnology, Cloud Computing, Software
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Sony Biotechnology
An innovative provider of high quality flow cytometry and imaging products to support advanced biomedical research.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Manufacturing, Pharmaceutical
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ProteinSimple
digital imaging systems
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Medical, Medical Device
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ViridisChem
SaaS, AI powered software platform offering toxicity evaluation of any chemical, formulations/mixtures, and development processes.
Founder(s):
Location: San Jose, California, United States
Industries: Artificial Intelligence, Biotechnology, Life Science, Machine Learning, Medical
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Murdock Martell, Inc
Specialized finance, accounting and HR solutions on demand
Founder(s): Claire Martell, Leslie Murdock
Location: San Jose, California, United States
Industries: Accounting, Biotechnology, Consulting, Finance
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CPC Scientific
CPC Scientific helps pharmaceutical and biotechnology companies in synthetic peptide production and therapeutic development.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Pharmaceutical, Product Research, Project Management
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Kuveda
Kuveda provides oncologists with SaaS-based tools and services for the analysis of cancer patients’ molecular profiles.
Founder(s):
Location: San Jose, California, United States
Industries: Big Data, Biotechnology, Genetics, Health Care, Information Technology
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BrighTex Bio-Photonics
BrighTex Bio-Photonics is an artificial intelligence company that provides services to skin science, research, and companies.
Founder(s):
Location: San Jose, California, United States
Industries: Artificial Intelligence, Biotechnology, Health Care
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CCS Associates
CCSA provides scientific advisory services in pharmaceutical, device discovery, development to government agencies and biotech companies.
Founder(s): Caroline C. Sigman
Location: San Jose, California, United States
Industries: Biotechnology, Consulting, Pharmaceutical, Risk Management, Therapeutics
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Bioelectric Devices
Bioelectric Devices is an electronics company developing artificial intelligence-driven bioelectronics technology.
Founder(s): Russell Potts
Location: San Jose, California, United States
Industries: Artificial Intelligence, Biotechnology, Electronics
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BioMarker Pharmaceuticals
BioMarker is a personalized health and wellness company that provides both products and services.
Founder(s):
Location: San Jose, California, United States
Industries: Biopharma, Biotechnology, Health Care, Pharmaceutical
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CISBAY
Silicon Valley based microbial technology company Cisbay provides sustainable bioinnovative solutions to treat soil and water globally.
Founder(s):
Location: San Jose, California, United States
Industries: Agriculture, AgTech, Biotechnology
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Panther Orthopedics
Panther Orthopedics develops fixation solutions for orthopedic extremity applications of trauma and sports medicine.
Founder(s): Kathryn Stecco
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Manufacturing, Medical Device, mHealth
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Misceo Grand Technology
Comprehensive Real-time Monitoring: Empowering outpatient monitoring with timely diagnosis
Founder(s): Mahesh Galgalikar
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Health Diagnostics, Medical
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Tacere Therapeutics
Tacere Therapeutics develops therapies to identify and treat diseases.
Founder(s): John Monahan
Location: San Jose, California, United States
Industries: Biotechnology, Genetics
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Ampere Life Sciences
Ampere Life Sciences, Inc. engages in developing medical and functional foods targeting antioxidant deficiencies. Ampere Life Sciences,
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Developer Platform, Medical Device
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Vascular Designs
Vascular Designs, Inc. develops and markets medical devices for people suffering from life-threatening illnesses, such as cancer. The
Founder(s): Robert Goldman
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Medical Device
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Stratedigm
Stratedigm is a Biotechnology company located in San Jose.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Industrial Automation
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Juno Biomedical, Inc.
Juno Biomedical’s CELLTech technology could change the standard of care for survivors of stroke and traumatic brain injury.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Medical Device, Therapeutics
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SeaChange Pharmaceuticals
SeaChange develops chemoinformatic and statistical methods to uncover links between drug molecules and the biological targets.
Founder(s): Brian Shoichet, John Irwin, Michael Keiser
Location: San Jose, California, United States
Industries: Biopharma, Biotechnology, Medical, Pharmaceutical
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SeaChange Pharmaceuticals
SeaChange develops chemoinformatic and statistical methods to uncover links between drug molecules and the biological targets.
Founder(s): Brian Shoichet, John Irwin, Michael Keiser
Location: San Jose, California, United States
Industries: Biopharma, Biotechnology, Medical, Pharmaceutical
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PhyNexus
PhyNexus provides the power of chromatography in a pipette tip column for protein and plasmid purification.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Health Care
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MBX Research
Biotechnology Empowering Specialty Growers
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Cannabis, Farming, Home and Garden, Hydroponics
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Alverix
Alverix focuses on producing handheld reader devices with the accuracy and precision of laboratory instrumentation.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Electronics, Finance, Health Care, Hospital, Manufacturing
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BioVitesse
BioVitesse is a biotechnology company which engages in the development, manufacture, and marketing of automated in-process quality control.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology
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Advansta
Advansta is a biotechnology company that specializes in the production and sale of a wide range of novel protein characterization tools.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Delivery, Life Science, Product Design
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Wincere
Wincere is a leading clinical data management and clinical and statistical programming solutions.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Information Services, Information Technology, Medical
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Celtrix Pharmaceuticals
Celtrix Pharmaceuticals is a pharmaceutical company that provides low-cost and generic prescription drugs.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Pharmaceutical
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ABsize
ABsize Inc. is a nanotechnology / nanomedicine company.
Founder(s): Isamu Oh
Location: San Jose, California, United States
Industries: Biotechnology, Pharmaceutical
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Companion Health Technologies
Companion Health Technologies is a remote patient monitoring system that dramatically improves quality of life for seniors.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Medical Device
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Precigenome
Precigenome is an industrial engineering agency that manufactures analytical instruments, PCR assays, IVD systems and OEM solutions.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Industrial Engineering, Industrial Manufacturing, Manufacturing
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nCefalon Corporation
We provide solution to predict seizures and send early warnings for epilepsy patients to avoid serious injuries.
Founder(s): Caleb Chan, Frank Tam, Jeffrey Chung
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Life Science, Medical, Medical Device
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Clinimetrics
Clinimetrics is a pharmaceuticals company providing project management and clinical monitoring services.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Medical, Pharmaceutical
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zNano
zNano develops and commercializes wastewater filtration systems.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Manufacturing
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Altamont Pharmaceutical Holdings
Altamont Pharmaceutical Holdings is an investment management firm seeking to invest in small cap and publicly traded biotech companies.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Financial Services, Pharmaceutical, Venture Capital
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Showa Denko Materials America
Showa Denko Materials America deals with research and development based on biotechnology and a supplier of advanced components.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Chemical
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UCP Biosciences
UCP Biosciences supplies test cups, dip cards, saliva tests, cardiac makers, test strips, and u-readers for various infectious diseases.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Life Science
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United Medical Instruments
United medical is a delivring ultrasound expertise & solutins to thousands of statisfied clinicians & biomedical engineers around the world.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Health Care
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Clarity Synergy Solutions
Doctors led consulting group helping startups and venture capitalists navigate medical device & biotech innovation & investment decisions.
Founder(s): Faisal Mirza
Location: San Jose, California, United States
Industries: Bioinformatics, Biotechnology, Wearables
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GenomicLabs.org
GenomicLabs.org is a non-profit organization that focuses on medical research with the intention of curing cancer.
Founder(s):
Location: San Jose, California, United States
Industries: Association, Biotechnology, Non Profit
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Microsonic Systems
Microsonic Systems Inc. provides acoustics-based micro-fluidics instruments to biotech and pharmaceutical industries. It offers
Founder(s): Eric Yeatman
Location: San Jose, California, United States
Industries: Biotechnology, Manufacturing, Medical, Pharmaceutical
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Suture Ease
Suture Ease is a medical company that develops products for laparoscopic procedures.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Health Care, Life Science, Medical
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GliaMed
GliaMed is a development-stage biopharmaceutical company dedicated to the discovery and development of small molecule drugs which enhance
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Life Science, Pharmaceutical
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Clinimetrics Research Associates
Provides clinical research and development services to biotechnology, pharmaceutical, and medical device companies in the US and Canada.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology
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Medic Affairs Consulting
Medic Affairs Consulting offers translational medicine, clinical trial design, and health economics expertise in medical affairs.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Health Care
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Mariner Biomedical
Mariner Biomedical focuses on developing topical skin care therapies.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Cosmetics, Health Care, Medical
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MicroRite
MicroRite is a Consulting and Training Company helping Pharmaceuticals,Biotechnology ,Medical Devices and Drug-Device Combination Products.
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Consulting, Health Care, Training
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Mycroft Cognitive Sciences
Catalyst for Life-Saving Research
Founder(s):
Location: San Jose, California, United States
Industries: Biotechnology, Health Care
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