At Best Startup California we track over 300,000 Californian startups and over 1,500,000 people who hold key positions in these companies. We use this directory of startups to highlight top employees, founders and organisations we think deserve more appreciation than they are currently getting.
We’ve ranked the top 94 Health Care companies in South San Francisco, California. The companies, startups and institutions listed in this article are all exceptional companies, well worth a follow. We have included links to their websites, socials and CrunchBase (if you’re interested in their financials).
We selected the organisations listed in this article based on:
- Track record
- Executive leadership
- Market share
- Innovation
- ESG rating
Our Data – We source our data from OSINT (open source intelligence) and public directories such as Crunchbase, SemRush and many more. The data from these sources should be treated with a degree of caution and verified yourself.
Top Health Care Companies & Startups (South San Francisco, California)
Annexon Biosciences
Annexon Biosciences is a biotech company, discovering and developing novel therapeutics for neurodegenerative and autoimmune disorders.
Founder(s): Arnon Rosenthal, Ben Barres
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Health Diagnostics, Life Science, Therapeutics
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Catalyst Biosciences
Catalyst Biosciences is a drug R&D company creating catalytic biopharmaceutical products based on engineered human proteases.
Founder(s): Charles S. Craik, Christopher Thanos, Jack Nguyen, Sandra Waugh Ruggles
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Life Science, Medical, Medical Device, Pharmaceutical, Therapeutics
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Nkarta Therapeutics
Nkarta Therapeutics is a developer of cell engineering platform created to build the next generation of cell therapies.
Founder(s): Paul Hastings
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care
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Earli
Earli is a developer of cancer treatment devices designed to search for natural biomarkers.
Founder(s): Cyriac Roeding, David Suhy, Sanjiv Gambhir
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical
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ESCAPE Bio
ESCAPE Bio is a clinical-stage biopharmaceutical company that develops small molecule drugs intended to treat neurodegenerative diseases.
Founder(s): Yadong Huang
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical
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ORIC Pharmaceuticals
ORIC Pharmaceuticals operates as a biopharmaceutical company.
Founder(s): Charles Sawyers, Scott Lowe
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Pharmaceutical, Therapeutics
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Interline Therapeutics
Interline Therapeutics is a drug discovery platform that enables the company to map and correct dysfunctional protein communities.
Founder(s): Zach Sweeney
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical, Therapeutics
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Zipline
Zipline designs, manufactures, and operates drones to deliver vital medical products to everyone, no matter where they live.
Founder(s): Keenan Wyrobek, Keller Rinaudo, Will Hetzler
Location: South San Francisco, California, United States
Industries: Delivery, Drones, Electric Vehicle, Home Health Care, Logistics, Robotics, Supply Chain Management
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Blade Therapeutics
Blade Therapeutics is a discovery stage drug development company.
Founder(s): Harry Dietz
Location: South San Francisco, California, United States
Industries: Biopharma, Health Care, Pharmaceutical, Therapeutics
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Prothena
Prothena is a clinical-stage neuroscience company focused on the discovery and development of novel therapies.
Founder(s): Dennis Selkoe
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Health Diagnostics
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Theravance Biopharma
Theravance Biopharma is a biopharmaceutical company with one approved product.
Founder(s): George Whitesides
Location: South San Francisco, California, United States
Industries: Biopharma, Biotechnology, Health Care, Medical, Pharmaceutical
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Rapt Therapeutics
Rapt is focused on the discovery and development of novel small-molecule agents to activate the immune system to eradicate cancer.
Founder(s): Brian Wong
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical, Pharmaceutical, Therapeutics
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Surrozen
Surrozen is a biopharmaceutical that focuses on unlocking the body’s regenerative power to treat injury and disease.
Founder(s): Calvin Kuo, Claudia Janda, Hans Clevers, K. Christopher Garcia, Roel Nusse
Location: South San Francisco, California, United States
Industries: Biotechnology, Emergency Medicine, Health Care
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Zenflow
Zenflow is a medical company that gives new hope to men suffering from BPH symptoms.
Founder(s): Nick Damiano, Shreya Mehta
Location: South San Francisco, California, United States
Industries: Health Care, Medical Device, Therapeutics
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Nura Bio
Nura Bio revolutionizes the treatment of neurological diseases with novel, life-changing neuroprotective medicines.
Founder(s): Andrew Pieper, Marc Freeman, Steven McKnight
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical, Wellness
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Mirvie
Mirvie is a biotech company that creates precise, actionable, and non-invasive tests for maternal-fetal health.
Founder(s): Maneesh Jain
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Health Diagnostics
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Amphivena Therapeutics
Amphivena Therapeutics is a clinical-stage immuno-oncology company that develops a platform of dual-function biologics.
Founder(s): Luke Evnin
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Therapeutics
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Achaogen
Achaogen, a biopharmaceutical company, discovers and develops broad-spectrum antibiotics to treat multi-drug resistant bacterial infections.
Founder(s): Kevin Judice, Nathaniel David
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical
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Kezar Life Sciences
Kezar Life Sciences company focused on the discovery and development of drugs targeting protein homeostasis for autoimmune disorders
Founder(s): Christopher Kirk, Jack Taunton, John Fowler
Location: South San Francisco, California, United States
Industries: Health Care, Health Diagnostics, Life Science, Therapeutics
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Chimera Bioengineering
Chimera solves the challenges of CARs with drug-responsive gene regulators, which allow us to re-program of the immune system.
Founder(s): Benjamin Wang, Christina Smolke, Gusti Zeiner
Location: South San Francisco, California, United States
Industries: Bioinformatics, Biotechnology, Genetics, Health Care
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Threshold Pharmaceuticals
Threshold Pharmaceuticals is focused on the development of drugs targeting Tumor Hypoxia, a low oxygen condition found in solid tumors.
Founder(s): George F. Tidmarsh
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Pharmaceutical
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Lyell Immunopharma
Lyell Immunopharma is an operator of a biotechnology company that develops cellular therapies to cure cancer.
Founder(s): Rick Klausner, Scott Boyken
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical, Pharmaceutical
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Sunesis Pharmaceuticals
Sunesis Pharmaceuticals is focused on the R&D of oncology therapeutics for the treatment of solid and hematologic cancers.
Founder(s): James Wells
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Pharmaceutical
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True North Therapeutics
True North Therapeutics is a pioneering biotechnology company selectively inhibiting the Complement pathway for diseases.
Founder(s): Nancy Stagliano
Location: South San Francisco, California, United States
Industries: Biotechnology, Clinical Trials, Health Care
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MiNDERA Corporation
MiNDERA Dx conducts research and development on non-invasive molecular testing for skin cancer and other skin diseases.
Founder(s): Philippe Nore, Tahir Mahmood, Tobin Dickerson
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical
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Crescendo Bioscience
Crescendo Bioscience develops diagnostic tools to provide rheumatologists with clinical insights to autoimmune and inflammatory disease.
Founder(s): Michael Centola
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical
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Cortexyme
Cortexyme is developing treatments for Alzheimer’s and other degenerative disorders.
Founder(s): Casey Lynch, Kristen Gafric, Stephen Dominy
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical, Pharmaceutical
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Atara Biotherapeutics
Atara Biotherapeutics (Nasdaq: ATRA) is an off-the-shelf, allogeneic T-cell immunotherapy company.
Founder(s): Isaac Ciechanover
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Therapeutics
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Veracyte
Veracyte develops molecular diagnostic tests to improve patient outcomes and lower healthcare costs.
Founder(s): Bonnie Anderson
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Health Diagnostics
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IDEAYA Biosciences
IDEAYA Biosciences is an oncology-focused biotechnology company committed to the discovery of breakthrough synthetic lethality
Founder(s): Jeffrey Hager, Yujiro S. Hata
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Therapeutics
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Cytokinetics
Cytokinetics is a biopharmaceutical company developing therapies for debilitating diseases.
Founder(s): James Sabry, James Spudich, Lawrence Goldstein, Ronald Vale
Location: South San Francisco, California, United States
Industries: Biopharma, Biotechnology, Health Care
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InterVene
InterVene is an up and coming medical device start-up company reinventing the way physicians treat severe venous disease in the legs.
Founder(s): Fletcher Wilson
Location: South San Francisco, California, United States
Industries: Health Care, Medical, Medical Device
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ShouTi
ShouTi specializes in the discovery and development of drugs against a type of targets called GPCR.
Founder(s): Raymond Stevens
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical, Pharmaceutical, Product Research
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diaDexus
diaDexus is a biotechnology company focused on the development and commercialization of diagnostic products with high clinical value.
Founder(s):
Location: South San Francisco, California, United States
Industries: Biotechnology, Clinical Trials, Health Care, Health Diagnostics
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EpiBiome
A precision microbiome engineering company developing alternatives to small-molecule antibiotics for use in agriculture and human health.
Founder(s): Aeron Tynes Hammack, Christina Tsai, Hsiao Lee, Nick Conley
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care
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Encoded Therapeutics
Encoded Therapeutics is a Harnessing the regulatory genome to create next-generation molecular therapies.
Founder(s): Kartik Ramamoorthi, Stephanie Tagliatela
Location: South San Francisco, California, United States
Industries: Biotechnology, Genetics, Health Care, Therapeutics
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Genome Medical
Genome Medical is a telegenomics technology and services company allowing access to genomic-based medicine.
Founder(s): Lisa Alderson, Randy Scott, Robert Green
Location: South San Francisco, California, United States
Industries: Genetics, Health Care, Life Science, Medical
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iPierian
iPierian is a drug discovery platform that develops therapies for neurodegenerative diseases such as SMA, ALS, and Parkinson’s.
Founder(s): Deepak Srivastava, George Daley
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical Device
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OmniVis
Put the power of the lab in the palm of your hand
Founder(s): Katherine Clayton
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Humanitarian, Information Technology, Software
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Jungla
We increasingly look to our genomes for answers. Jungla is committed to ensuring we find them.
Founder(s): Alexandre Colavin, Carlos Araya, Jason Reuter
Location: South San Francisco, California, United States
Industries: Biotechnology, Genetics, Health Care, Health Diagnostics
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Vera Therapeutics
Vera Therapeutics is a biotechnology company developing innovative biologic therapeutics with transformative clinical potential.
Founder(s): Marshall Fordyce
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care
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Pliant Therapeutics
Pliant Therapeutics focuses on discovering, developing, and commercializing breakthrough treatments for fibrotic diseases.
Founder(s): Bill DeGrado, Bradley Backes, Dean Sheppard, Hal Chapman
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Health Diagnostics, Pharmaceutical, Recruiting, Therapeutics
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Senti Biosciences
Senti Biosciences is a developer of a programmable biology platform for cancer therapies.
Founder(s): Jim Collins, Philip Lee, Timothy K. Lu, Wilson Wong
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical, Therapeutics
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CytomX Therapeutics
CytomX Therapeutics is a biotechnology company that focuses on developing proteolytically-activated antibodies.
Founder(s): Fred Gluck, Patrick Daugherty
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Pharmaceutical, Therapeutics
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Carrum Health
Carrum Health is a value-based Centers of Excellence platform that ensures patients receive higher-quality and less expensive care.
Founder(s): Brent Nicholson, Sach Jain
Location: South San Francisco, California, United States
Industries: Health Care, Hospital, Marketplace
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Harpoon Therapeutics
Harpoon Therapeutics is a clinical-stage immunotherapy company developing novel T cell engagers (TriTACs) for the treatment of cancer.
Founder(s): Luke Evnin, Patrick Baeuerle
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Therapeutics
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Nodality
Nodality develops biologically-informed clinical treatments for patients with cancer and autoimmune diseases.
Founder(s): Garry P Nolan, Omar D. Perez
Location: South San Francisco, California, United States
Industries: Biotechnology, Clinical Trials, Health Care, Health Diagnostics
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RevMAb Biosciences
RevMAb Biosciences is biotechnology company that focuses on the developing of goat and rabbit monoclonal antibodies.
Founder(s):
Location: South San Francisco, California, United States
Industries: Biotechnology, Customer Service, Health Care, Medical Device
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Day One Biopharmaceuticals
Day One Biopharmaceuticals is a biotechnology company that focuses on developing new cancer therapies for patients of all ages.
Founder(s): Julie Papanek Grant, Samuel Blackman
Location: South San Francisco, California, United States
Industries: Biopharma, Biotechnology, Health Care, Pharmaceutical
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Counsyl
Counsyl is a health technology company that offers DNA screening for men, women, and their children.
Founder(s): Balaji Srinivasan, Eric Evans, Ramji Srinivasan, Rishi Kacker
Location: South San Francisco, California, United States
Industries: Biotechnology, Genetics, Health Care, Health Diagnostics, Medical
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Biomimedica
Biomimedica is a medical device company that is pioneering new approaches to repair joints through synthetic cartilage technology.
Founder(s): David Myung, Eric J. Kim, Lampros Kourtis
Location: South San Francisco, California, United States
Industries: Health Care, Medical, Medical Device
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CoMentis
CoMentis is a biotech company engaged in the research and development of small molecule drugs to treat neurovascular diseases.
Founder(s): Ken Kengatharan
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical
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SmartPhage
SmartPhage is a Health Care company.
Founder(s): Jacob Shiach
Location: South San Francisco, California, United States
Industries: Health Care
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Tradewind BioScience
Tradewind BioScience is a biotechnology company developing antibody therapeutics for ovarian cancer.
Founder(s): Ron Buckanovich, Thaddeus Allen
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical
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DoctorsForMe Inc
Help patients with complex conditions find the right doctors.
Founder(s): Wei-Wu He
Location: South San Francisco, California, United States
Industries: Analytics, Health Care, Medical
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Epic-Bio
Epic Bio’s strength is a relentless focus on ushering in a new era of gene regulation.
Founder(s):
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care
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Hyperion Therapeutics
Hyperion Therapeutics is a biopharmaceutical company focused on creating treatments for urea cycle disorders and other rare diseases.
Founder(s): Mark Blumling
Location: South San Francisco, California, United States
Industries: Biopharma, Biotechnology, Health Care, Therapeutics
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Monogram Biosciences
Treatment for Diseases and Cancers
Founder(s):
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care
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R2M Pharma
R2M Pharma helps in accelerating drug discovery by leveraging an experienced group of skilled scientists and strategic partners.
Founder(s): Julio Medina
Location: South San Francisco, California, United States
Industries: Biotechnology, Clinical Trials, Health Care, Medical, Pharmaceutical
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Adamant Technologies
Adamant Technologies builds smartphone accessories that can interpret odors.
Founder(s):
Location: South San Francisco, California, United States
Industries: Electronics, Fitness, Health Care, Software
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Anesiva
Anesiva, Inc., a biopharmaceutical company, engages in the development and commercialization of novel therapeutic treatments for pain
Founder(s): John McLaughlin
Location: South San Francisco, California, United States
Industries: Biotechnology, Genetics, Health Care, Medical, Therapeutics
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Gryphon Bio, Inc.
Precision Medicine
Founder(s): Kevin Wang, PhD, Will Haskins, PhD
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care
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Cerimon Pharmaceuticals
Cerimon Pharmaceuticals develops and commercializes therapeutics for autoimmune diseases, inflammation, and pains.
Founder(s): Ansbert Gadicke, Luke Evnin, Paul Sekhri
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Pharmaceutical, Therapeutics
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TrueMed
TrueMed provides healthcare services such as home health care, palliative care, orthopedic rehabilitation and wound care program.
Founder(s):
Location: South San Francisco, California, United States
Industries: Health Care, Home Health Care, Medical
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TerraVia – Assets
TerraVia is a next-generation food, nutrition and specialty ingredients company that harnesses the power of algae.
Founder(s):
Location: South San Francisco, California, United States
Industries: Food and Beverage, Health Care, Medical
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Parvus Therapeutics
Parvus Therapeutics is a novel class of therapeutics to reverse autoimmune disease without impairing normal immunity.
Founder(s):
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Therapeutics, Wellness
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ProNeurotech
ProNeurotech is a developer of neuroprotective drugs that prevent axon loss after acute injury or chronic degenerative disease.
Founder(s):
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Neuroscience
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Oncology Therapeutics Network
Oncology Therapeutics Network
Founder(s):
Location: South San Francisco, California, United States
Industries: Health Care, Medical, Therapeutics
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Proteolix
Onyx Pharmaceuticals (NASDAQ: ONXX) is a biopharmaceutical company engaged in the development and commercialization of innovative therapies
Founder(s): Dean Grad, Jeffery W. Kelly, Phil Whitcome, Ray Deshaies, Raymond Deshaies
Location: South San Francisco, California, United States
Industries: Biopharma, Biotechnology, Health Care, Pharmaceutical
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Centivax
Centivax is a healthcare based agency that provides biotechnology, pharmaceutical, medical device manufacturing and therapeutics services.
Founder(s):
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Health Diagnostics, Medical
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BOYDSense
BOYDSense specializes in developing non-invasive and affordable tools for measuring critical biomarkers via the exhaled breath.
Founder(s): Bruno Thuillier
Location: South San Francisco, California, United States
Industries: Health Care, Health Diagnostics, Medical Device
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Toft Group
Toft Group is a global recruiting firm for healthcare and life-sciences industries.
Founder(s):
Location: South San Francisco, California, United States
Industries: Biotechnology, Consulting, Health Care, Medical
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Digenomix
Digenomix is a biotechnology company that offers single-cell genome sequencing services.
Founder(s):
Location: South San Francisco, California, United States
Industries: Biotechnology, Genetics, Health Care
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Distributed Bio
Distributed Bio is an immuno-engineering company that provides computational tools, antibody libraries, and more.
Founder(s): Giles Day, Jacob Glanville
Location: South San Francisco, California, United States
Industries: Bioinformatics, Biotechnology, Cloud Computing, Health Care, Pharmaceutical
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American Technologies Network, Corp.
American Technologies Network, Corp. is focused on manufacturing advanced HD optics, thermal imaging optics and night vision devices.
Founder(s):
Location: South San Francisco, California, United States
Industries: Health Care, Manufacturing
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BayBio
BayBio is a life science association and company based in Northern California.
Founder(s):
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical
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WideTrial
WideTrial is a third-party sponsor of group-level Expanded Access programs (EAPs).
Founder(s):
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care
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QLSF Biotherapeutics
QLSF Biotherapeutics is an immuno-oncology startup company.
Founder(s): Hieu Van Tran, Shihao Chen
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Life Science, Medical
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OrganOmics
OrganOmics engages in drug discovery rooted in precision medicine.
Founder(s):
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Medical, Therapeutics
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Biospect
Biospect Inc., a South San Francisco-based life sciences company launched last year to detect protein biomarker patterns.
Founder(s):
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Life Science
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Berg Communities
Berg Senior Services offers premier assisted living and memory care in four locations throughout the Bay Area.
Founder(s):
Location: South San Francisco, California, United States
Industries: Consulting, Health Care
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Speech Goals Speech Therapy
Speech Goals Speech Therapy is a pediatric speech and early intervention therapy company specialized in autism spectrum disorder and more.
Founder(s):
Location: South San Francisco, California, United States
Industries: Child Care, Health Care, Service Industry
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BioMark Health
Better outcomes with better data.
Founder(s):
Location: South San Francisco, California, United States
Industries: Analytics, Health Care, Information Technology, Machine Learning
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Health Plan of San Mateo
Health Plan of San Mateo is a non-profit organization that offers health care services.
Founder(s):
Location: South San Francisco, California, United States
Industries: Health Care, Medical, Non Profit
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Altheos
Altheos was a biopharmaceutical company focused on the development of small molecule drugs.
Founder(s): Henry H. Hsu, Ken Kengatharan
Location: South San Francisco, California, United States
Industries: Biotechnology, Clinical Trials, Health Care
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Global Solutions for Infectious Diseases
GSID) is a non-profit global health organization engaged in the development of diagnostic and preventive tools for infectious diseases.
Founder(s): Seung Il Shin
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care
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Image Orthodontics
Image Orthodontics is a health & wellness company specializing in orthodontic care services.
Founder(s):
Location: South San Francisco, California, United States
Industries: Fitness, Health Care
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Vital Restoration
Vital Restoration is a restoration company focusing on residential and commercial interior damages.
Founder(s):
Location: South San Francisco, California, United States
Industries: Health Care, Real Estate
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The Clinical Development of Carfilzomib
Carfilzomib is a second-generation proteasome inhibitor that is being investigated as a potential treatment for patients .
Founder(s):
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care
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AAA Wholesale Company
AAA Wholesale Company’s mission is to provide the one-stop resource to healthcare professionals.
Founder(s):
Location: South San Francisco, California, United States
Industries: Consulting, Health Care, Medical, Pharmaceutical, Wholesale
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Freenome
Freenome is a biotechnology company with a comprehensive multiomics platform for cancer detection using a routine blood draw.
Founder(s): Charles Roberts, Gabriel Otte, Michael Otte, Riley Ennis
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Health Diagnostics, Personal Health
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Complete Linen Services
Complete Linen Services offer a full range of laundry and linen services for hospitality, healthcare and rental needs.
Founder(s):
Location: South San Francisco, California, United States
Industries: Consumer, Facilities Support Services, Health Care, Laundry and Dry-cleaning
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Compound Focus
Compound Focus, Inc. offers molecule compound management services for liquid and solid compounds.
Founder(s):
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care
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Torix Medical
Torix Medical has created the Innoflow device, a disruptive solution.
Founder(s):
Location: South San Francisco, California, United States
Industries: Biotechnology, Health Care, Life Science, Medical, Medical Device
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